The idea behind designing a grid-based website is typically for visual and structural balance.
Having a more sophisticated structure offers more flexibility and could also further enhance the visual and user experience for visitors. In fact, users have an easier time following the consistency of a grid-base page as our brains are more receptive to grid layouts. Here are a few websites to draw inspiration from for your next design project.
UX Magazine
Design made in Germany
Made by Many (SXSW)
Pentagram
D&AD Student Awards
Tokyo ID
Iventory Studio
Blake Allen Design
Toko
Area 22